Fig. 2From: Bleomycin induces senescence and repression of DNA repair via downregulation of Rad51Bleomycin treatment induces sustained DNA damage. A A549 cells were exposed to bleomycin at a dose of 10 ΟM, followed by immunostaining for ÎłH2AX foci (red) at indicated time points. B A549 cells were treated with bleomycin (10 ΟM) for the indicated time points, and then a comet assay was performed using neutral electrophoresis. C Cell cycle distributions were examined by flow cytometry after 1, 2, and 3 days of bleomycin exposure (10 ΟM). Significance markers: *pâ<â0.05; **pâ<â0.01 compared to control; nâ=â3Back to article page