Table 1 Antibodies to glutamate receptor subunits in paraneoplastic neurodegenerative syndrome patient sera as revealed by immunohistochemistry, Western blot analysis, transfected cells, and electrophysiology
Patient | Antibody Type | Tumor | Pattern of GluR Receptor Staining | Western Blot Analysis | Transfected Cells | Electrophysiology |
|---|---|---|---|---|---|---|
1 | I | Transitional cell, bladder | R1 | R5 | R1, R6 | Enhanced |
2 | IIa | Small cell, lung | None | None | None | None |
3 | IIb | Breast | None | None | R4 | Enhanced |
4 | IIa | Small cell, lung | None | None | None | None |
5 | I | Unknown | None | None | R1 (Faint R3, R6, R4) | Enhanced |
6 | I | Ovary | None | None | R6 | None |
7 | IIb | Breast | None | None | R6 | Enhanced |
Control | None | None | None | None | None | None |