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Table 1 Antibodies to glutamate receptor subunits in paraneoplastic neurodegenerative syndrome patient sera as revealed by immunohistochemistry, Western blot analysis, transfected cells, and electrophysiology

From: Autoantibodies to Neuronal Glutamate Receptors in Patients with Paraneoplastic Neurodegenerative Syndrome Enhance Receptor Activation

Patient Antibody Type Tumor Pattern of GluR Receptor Staining Western Blot Analysis Transfected Cells Electrophysiology
1 I Transitional cell, bladder R1 R5 R1, R6 Enhanced
2 IIa Small cell, lung None None None None
3 IIb Breast None None R4 Enhanced
4 IIa Small cell, lung None None None None
5 I Unknown None None R1 (Faint R3, R6, R4) Enhanced
6 I Ovary None None R6 None
7 IIb Breast None None R6 Enhanced
Control None None None None None None