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Fig. 9 | Molecular Medicine

Fig. 9

From: An Inhibitor of Macrophage Arginine Transport and Nitric Oxide Production (CNI-1493) Prevents Acute Inflammation and Endotoxin Lethality

Fig. 9

Histological appearance of paw tissues obtained from the carrageenan-injected pawa

Three hours after carrageenan administration, paw tissues were fixed with 10% formalin, and sections were stained with hematoxylin and eosin. (a and b) Sections taken from the carrageenan-treated footpad of a control animal not receiving CNI-1493. (a) A low power panoramic view; (b) a high power view of the same tissue showing neutrophil margination in a dilated capillary, (c and d) Comparable sections taken from the carrageenantreated footpad of an animal treated with CNI-1493 (10 mg/kg, i.p.).

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Molecular Medicine

ISSN: 1528-3658