Histological appearance of paw tissues obtained from the carrageenan-injected pawa
Three hours after carrageenan administration, paw tissues were fixed with 10% formalin, and sections were stained with hematoxylin and eosin. (a and b) Sections taken from the carrageenan-treated footpad of a control animal not receiving CNI-1493. (a) A low power panoramic view; (b) a high power view of the same tissue showing neutrophil margination in a dilated capillary, (c and d) Comparable sections taken from the carrageenantreated footpad of an animal treated with CNI-1493 (10 mg/kg, i.p.).