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Fig. 5 | Molecular Medicine

Fig. 5

From: Construction of a Novel Bifunctional Biogenic Amine Receptor by Two Point Mutations of the H2-Histamine Receptor

Fig. 5

Effect of epinephrine on inositol trisphosphate (IP3) generation in Hepa cells transfected with the wild-type and Ala 186 -Ser 187 mutant H2-histamine receptor

Epinephrine at a maximal concentration of 10−5 M induced a time-dependent increase in IP3 generation in Hepa cells expressing the mutant Ala186-Ser187 H2-histamine receptor but had no such effect on nontransfected Hepa cells. Data are represented as means ± SEM, n = 4.

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