Effect of H-0294 on HIV-1 replication in activated PBLs
RT activity in culture supernatants was assessed at the indicated days postinfection as described in Materials and Methods. Cultures were infected and maintained under concentrations of H-0294 as indicated (key indicating concentrations in Panel A applies to Panel B as well). (A) Cultures were infected with HIV-1ADA at MOI of 10 ng p24/106 cells. (B) Cultures were infected with HIV-1ADA at MOI of 1 ng p24/106 cells. Note difference in y-axis scales between Panels A and B.