Fig. 4

The effect of thalidomide treatment on weight gain

Weight gain is expressed as the mean of the percent of body weight gained relative to starting weight ± one SEM for 21 patients treated for 14 days with MDT and 300 mg/day of thalidomide (●) and eight patients treated for 14 days with MDT and placebo (▲). The arrow above the figure denotes the duration of treatment with thalidomide or placebo. On Days 15 and 21, weight gain in all thalidomide-treated patients was significantly higher than that of placebo-treated patients (p = 0.003 and 0.04, respectively).