| Thalidomide treatment (n = 18)a | Placebo treatment (n = 8)a |
---|
Cytokine | Pre | Mid | Post | Pre | Mid | Post |
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TNFα | 1871 ± 601 | 1274 ± 565 | 2504 ± 793 | 1875 ± 797 | 2283 ± 775 | 1815 ± 790 |
IFNγ | 218 ± 122 | 549 ± 330 | 218 ± 58 | 197 ± 69 | 236 ± 79 | 231 ± 55 |
- TNFα and IFNγ levels were assayed by ELISA (as described in Materials and Methods) in the supernatants of PBMCs obtained from patients treated with either thalidomide or placebo. Results are expressed as pg/ml. aThe means for the number of patients shown in the parentheses ± SEM are given.