Fig. 5
From: Antiviral Drugs from the Nucleoside Analog Family Block Volume-Activated Chloride Channels
Cell volume measurements in NIH 3T3 fibroblasts in the presence and absence of AZT and in fibroblasts infected with HSV in the presence and absence of AZT
The absolute cell volumes (in pl) were measured 12, 24, and 34 hr after reculturing the cells. Conditions were changed immediately before the time point of 12 hr. At this point cells were exposed to AZT, virus (HSV at an m.o.i. of >10) or both. For controls the cell volumes of untreated cells were measured at the equivalent time points.