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Fig. 1 | Molecular Medicine

Fig. 1

From: The MarR Repressor of the Multiple Antibiotic Resistance (mar) Operon in Escherichia coli: Prototypic Member of a Family of Bacterial Regulatory Proteins Involved in Sensing Phenolic Compounds

Fig. 1

Genetic organization of the marRAB operon

MarR is an autorepressor that normally maintains mar operon expression at a low level. In the presence of inducers such as salicylate (SAL), MarR repressor activity is antagonized, resulting in increased levels of MarA and, consequently, increased antibiotic resistance.

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Molecular Medicine

ISSN: 1528-3658