Table 4 Summary of mutations in BL and various B cell subsets
From: Burkitt’s Lymphoma Is a Malignancy of Mature B Cells Expressing Somatically Mutated V Region Genes
Cell Population | n a | Range | % Mutation | Reference |
|---|---|---|---|---|
Endemic Burkitt | 5 | 13–29 | 6.0 | Present Work |
Sporadic Burkitt | 7 | 0–13 | 1.8 | Present Work |
μ+δ+ PBL | 16 | 0–3 | 0.2 | 15;b |
μ-Only PBL | 28 | 0–13 | 1.9 | 15;b |
Class-Switched PBL | 12 | 3–23 | 4.0 | 15;b |
μ-Expressing GCC | 8 | 1–10 | 2.0 | 16 |
Class-Switched GCC | 9 | 1–13 | 3.3 | 16 |