Fig. 10
From: Taxol-Induced Mitotic Block Triggers Rapid Onset of a p53-Independent Apoptotic Pathway
At µ M taxol concentrations, both p53-expressing and -null MEFs exhibit a similar taxol-induced decline in cell number
Normal p53-expressing (A) and p53-null (B) MEFs grown in 48-well plates were treated with 1 µM (◇), 250 nM (○), 150 nM (△) 100 nM (⊞), 50 nM (◆), 25 nM (—●—), or 0 (□) taxol and both adherent and detached cells in triplicate wells were counted at the indicated time intervals. Data is plotted as log cell number.