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Table 1 Blood glucose concentration mg/100 m (mean ± SEM) in hIAPP transgenic and nontransgenic litter mates, before and during long-term treatment with glucocorticosteroid

From: Amyloid Formation in Response to β Cell Stress Occurs In Vitro, but Not In Vivo, in Islets of Transgenic Mice Expressing Human Islet Amyloid Polypeptide

Day Transgenic Mice Nontransgenic Mice
Fasting   
0 67.1 73.6
  2.4 4.1
  n = 11 n = 10
Fed   
0 117.2 126.8
  5.2 4.5
  n = 11 n = 10
60 206.4a 214.8a
  4.5 3.1
  n = 11 n = 10
130 214.5b 217.3b
  3.4 3.8
  n = 8 n = 7
170 219.6b 222.1
  3.6 4.7
  n = 8 n = 7
185 220.0 221.8
  6.0 10.8
  n = 4 n = 4
  1. ap < 0.001 versus Day 0
  2. bp < 0.05 versus Day 60.