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Table 4 HLA-A24 frequency in DR phenotypes and age at diagnosis of diabetes mellitus: unrelated IDDM subjects

From: Analysis of Families at Risk for Insulin-Dependent Diabetes Mellitus Reveals that HLA Antigens Influence Progression to Clinical Disease

Phenotype

Frequency HLA-A24

Mean Age at Diagnosis of Diabetes

n

%

A24+

A24−

DR3,4

21/107

20

13.1 ± 5.8

15.9 ± 10.3

DR3,3

2/26

8

24.5 ± 9.5

16.5 ± 11.2

DR4,4

4/24

17

7.0 ± 2.9

20.4 ± 10.9a

DR4,X

11/64

17

13.9 ± 10.4

20.4 ± 12.5

DR3,X

3/22

14

11.7 ± 6.8

24.3 ± 11.5b

DRX,X

7/27

26

31.1 ± 11.9

24.3 ± 12.3

  1. p values, Wilcoxon rank sum test, a<0.005, b<0.05.