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Fig. 7 | Molecular Medicine

Fig. 7

From: Interleukin 1 Induces HIV-1 Expression in Chronically Infected U1 Cells: Blockade by Interleukin 1 Receptor Antagonist and Tumor Necrosis Factor Binding Protein Type 1

Fig. 7

IL-1 enhances TNFα-induced p24 antigen production

(A) U1 cells were treated with RPMI () or 5 ng/ml IL-1β () immediately prior to the addition of different concentrations of TNFα. After 24 hr, p24 antigen concentrations were determined by ELISA. (B) U1 cells were cultured in the absence or presence of 5 ng/ml IL-1β for 24 hr before the addition of 10 ng/ml TNFα. All cultures were assayed for p24 antigen 24 hr following the addition of TNFα. p ≤ 0.01; and §p ≤ 0.001 when comparing cells stimulated with both IL-1β and TNFα with cells stimulated with TNFα alone.

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