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Table 1 Total nitrogen oxide and cGMP production by porcine arterial segments

From: Vascular Gene Transfer of the Human Inducible Nitric Oxide Synthase: Characterization of Activity and Effects on Myointimal Hyperplasia

Treatment Groups Total \({\bf{NO}}_2^ - \) and \({\bf{NO}}_3^ - \) (pmol/mg/24 hr) p Value a (ANOVA) cGMP (fmol/mg/24 hr) p Value ‡ (ANOVA)
Control 29.7 ± 6.5b — 5.2 ± 2.8 —
Injury alone 35.4 ± 8.4 NSC 7.3 ± 3.4 NS
Injury + MFGlacZ 40.1 ± 5.2 NS 6.8 ± 2.9 NS
Injury + DFGiNOS 121.9 ± 43.1 0.001 101.3 ± 12.1 0.002
Injury + DFGiNOS + L-NMA 37.4 ± 8.2 NS 5.6 ± 4.2 NS
  1. aVersus uninjured control arterial segments.
  2. bValues are means ± SD, n - 4, representative of three separate experiments.
  3. cNS, not significant.
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Molecular Medicine

ISSN: 1528-3658