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Table 1 Total nitrogen oxide and cGMP production by porcine arterial segments

From: Vascular Gene Transfer of the Human Inducible Nitric Oxide Synthase: Characterization of Activity and Effects on Myointimal Hyperplasia

Treatment Groups

Total \({\bf{NO}}_2^ - \) and \({\bf{NO}}_3^ - \) (pmol/mg/24 hr)

p Value a (ANOVA)

cGMP (fmol/mg/24 hr)

p Value ‡ (ANOVA)

Control

29.7 ± 6.5b

—

5.2 ± 2.8

—

Injury alone

35.4 ± 8.4

NSC

7.3 ± 3.4

NS

Injury + MFGlacZ

40.1 ± 5.2

NS

6.8 ± 2.9

NS

Injury + DFGiNOS

121.9 ± 43.1

0.001

101.3 ± 12.1

0.002

Injury + DFGiNOS + L-NMA

37.4 ± 8.2

NS

5.6 ± 4.2

NS

  1. aVersus uninjured control arterial segments.
  2. bValues are means ± SD, n - 4, representative of three separate experiments.
  3. cNS, not significant.
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Molecular Medicine

ISSN: 1528-3658