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Table 2 Constitutive secretion of CSF-1 and GM-CSF by genetically modified TEC is similar in several strains

From: Macrophage Growth Factors Introduced into the Kidney Initiate Renal Injury

TEC (Strain)

CSF-1 (CFU)

GM-CSF (CFU)

Uninf. (CFU)

C3H-++

66

46

4

MRL-++

63

30

4

MRL-lpr

68

39

3

  1. Culture supernatants (1 ml/5 × 105 TEC) were collected 1 month after retroviral infection. CSF-1 and GM-CSF were measured by colony stimulating assay as CFU per 105 bone marrow cells. Positive standard for the assay is MRL-lpr sera at 6 months of age, 53 ° 4 CFU. All values are means of duplicate samples. Uninf., retroviral uninfected TEC.