Molecular Medicine

Table 5 Implantation of 1 × 10 ⁶ CSF-1-TEC and GM-CSF-TEC is sufficient to induce maximal subcapsular and intrarenal lesions

From: Macrophage Growth Factors Introduced into the Kidney Initiate Renal Injury

Cell Number	CSF-1		GM-CSF
Cell Number	Subcapsular^a	Intrarenal^a	Subcapsular^a	Intrarenal^a
5 × 10⁶	37 ° 6^b	17 ° 4^b	59 ° 8^b	49 ° 2^b
1 × 10⁶	36 ° 5^b	20 ° 4^b	65 ° 10^b	45 ° 4^b
0.5 × 10⁶	25 ° 1	9 ° 3	22 ° 2	21 ° 3

^aSubcapsular and intrarenal cell infiltration was evaluated by counting the numbers of cell layers in an area with the greatest lesion. Histological examination: 28 days post-Ix. Recipient are MRL-lpr mice, 7 weeks of age. n = 3 in each group.
^bp < 0.05 versus 0.5 × 10⁶.

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ISSN: 1528-3658

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