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Table 7 To induce cell infiltration with CSF-1, recipient MRL- lpr mice need to be at least 6 weeks of age

From: Macrophage Growth Factors Introduced into the Kidney Initiate Renal Injury

TEC

Age

4 Weeks

6–8 Weeks

10–12 Weeks

20 Weeks

A. Subcapsular a

    

CSF-1

18 ° 2

37 ° 6b

29 ° 3b

25 ° 3b

GM-CSF

44 ° 5b,c

57 ° 8b,c

68 ° 13b,c

49 ° 6b,c

Uninf.

15 ° 4

12 ° 2

14 ° 2

12 ° 1

B. Intrarenal a

    

CSF-1

2 ° 2

17 ° 4b

14 ° 4b

15 ° 3b

GM-CSF

37 ° 16b,c

39 ° 6b,c

53 ° 13b,c

37 ° 11b,c

Uninf.

2 ° 2

1 ° 1

2 ° 2

2 ° 2

  1. aSubcapsular and intrarenal cell infiltration was evaluated by counting the numbers of cell layers in an area with the greatest lesion. Histological evaluation: 28 days post-Ix. Recipients were MRL-lpr mice. n = 3 in each group. Number of implanted cells: 1 × 106/mouse. Uninf., retroviral uninfected TEC.
  2. bp < 0.05 versus Uninf.
  3. cp < 0.05 versus CSF-1.