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Fig. 5 | Molecular Medicine

Fig. 5

From: Cyclooxygenase-2-Dependent Bronchoconstriction in Perfused Rat Lungs Exposed to Endotoxin

Fig. 5

Time course of LPS-induced bronchoconstriction (A) and TX release into the perfusate (B)

10 min before injection of LPS (50 µg/ml), lungs were pretreated with either 0.3 µM actinoymcin D (AcD) or with 100 µM cycloheximide (Chx). Data are expressed as means ± SEM; n = 3. R/Ro′, resistance normalized to time point 0. Please note that in these experiments lungs from male Sprague-Dawley rats were used.

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