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Table 1 Quantities of immunoreactive hGR α and hGR β in HeLa cells and their fractions a

From: The Non-Ligand Binding β-Isoform of the Human Glucocorticoid Receptor (hGRβ): Tissue Levels, Mechanism of Action, and Potential Physiologic Role

 

hGRα (fmol/µg protein)

hGRβ (fmol/µg protein)

Ratio α/β b

Whole cell

240.00

1032.00

0.23

Cytosol − dexamethasone

153.00

711.00

0.22

Cytosol + dexamethasone

120.00

561.00

0.21

Nucleus − dexamethasone

36.00

258.00

0.14

Nucleus + dexamethasone

54.00

288.00

0.19

  1. aData from one representative of two experiments.
  2. bThere was no significant difference in the α/β ratios in HeLa cells or their fractions in either experiment.