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Fig. 4 | Molecular Medicine

Fig. 4

From: CD3-ε Overexpressed in Prothymocytes Acts as an Oncogene

Fig. 4

Phenotypes of thymic lymphoid tumor cells isolated from double mutant mice.

(A) Flow cytometric analyses of tumor cells derived from RAG-2null × tgε26+/− mice. The cells were stained with antibodies against CD4 and CD8, and CD25 and CD44. Most of the tumors from these mice bear the phenotype represented by tumor #2.

(B) Flow cytometric analyses of tumor cells derived from lcknull × tgε26+/− mice. The cells were stained with antibodies against CD3, CD4, and CD8.

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