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Fig. 2 | Molecular Medicine

Fig. 2

From: The Genetic Defect Causing Huntington’s Disease: Repeated in Other Contexts?

Fig. 2

Duration of disease after onset and age at death versus number of HD CAG repeat units

Age at death (dotted circles) is plotted against the number of CAG repeats for 305 patients whose brains were subjected to postmortem analysis to confirm HD neuropathology (13). The line shows the predicted curve-fit (r2 = .49) based on a similar exponential model to that used Fig. 1. Also shown is the number of years between onset and death (shaded triangles) for 144 patients whose age at onset and death were both known. Linear regression analysis failed to identify any relationship between the disease duration and number of CAG repeat units.

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