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Table 1 V-region sequences isolated from the infiltrates A and B

From: Antigen-Dependent B Cell Differentiation in the Synovial Tissue of a Patient with Reactive Arthritis

  

Cluster A

Cluster B

Putative Germ-line Gene

No. of Isolated Sequences

Putative Germ-line Gene

No. of Isolated Sequences

Section 65

H chain

VH1

DP3

1

   
   

DP4

4

   
  

VH3

DP47

1a

   
   

DP49

6

   
  

VH4

DP71

2

   
   

DP71

1

   
   

DP71

1

   
 

L chain

Vλ2

DPL10

1

Vλ1

DPL2

3b

   

DPL11

2

 

DPL2

1

  

Vλ6

IGLV6S1

1

Vλ3

LV318

1

Section 66

H chain

VH1

DP7

1

VH3

DP53

2

   

DP10

2

VH7

VI-41b

1

   

DP14

4

   
   

DP75

1

   
  

VH3

DP31

1

   
   

DP35

1

   
   

DP42

2

   
   

DP47

1a

   
   

DP47

1

   
   

DP49

1

   
   

DP49

1

   
   

DP49

1

   
  

VH4

DP65

1

   
   

DP70

2

   
 

L chain

Vλ3

LV318

1

Vλ1

DPL2

3b

  

Vλ4

DPL16

1

 

DPL3

3

     

Vλ3

LV318

1

  

VκI

O12-O2

1c

Vλ4

DPL16

3

   

O18-O8

1c

 

DPL16

5

   

O18-O8

1

Vλ6

IGLV6S1

1

   

O18-O8

1

Vλ5

Unknown

3

  

Vκ3

B2

1c

   
  1. a Indicates identical VH rearrangement.
  2. b Indicates identical VL rearrangement.
  3. c Indicates out-of-frame V-to-J joining.