Table 2 Somatic mutations in synovial memory B cells
From: Antigen-Dependent B Cell Differentiation in the Synovial Tissue of a Patient with Reactive Arthritis
Mutations in CDR | |||||
|---|---|---|---|---|---|
VH/VL Sequences | No. of Mutations | R | S | R/S | |
65 A | 1.1 | 17 | 3 | 2 | 1.5 |
1.7 | 17 | 4 | — | ≥4 | |
3.3 | 14 | 5 | 1 | 5 | |
4.4 | 22 | 3 | 2 | 1.5 | |
4.2 | 25 | 4 | 1 | 4 | |
8.3 | 18 | 6 | 1 | 6 | |
66 A | 1.6 | 15 | 4 | 1 | 4 |
1.8 | 18 | 3 | 2 | 1.5 | |
1.15 | 25 | 7 | 3 | 2.5 | |
3.6 | 21 | 7 | 2 | 3.5 | |
5.4 | 25 | 8 | 3 | 2.7 | |
7.3 | 21 | 9 | 2 | 4.5 | |
7.4 | 11 | 5 | 1 | 5 | |
8.5 | 14 | 4 | 2 | 2 | |
65 B | 8.1 | 17 | 6 | 2 | 3 |
66 B | 1.2 | 28 | 7 | — | ≥7 |
8.6 | 19 | 7 | 5 | 1.4 | |