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Table 2 Characteristics of T0 human breast tumors

From: Expression of Molecular Biomarkers in Primary Breast Tumors Implanted into a Surrogate Host: Increased Levels of Cyclins Correlate with Tumor Progression

Tissue

Cyclin D1a

Cyclin D3a

Estrogen Receptora

p53a

C-erbB-2a

Xenograft Growthb

037

76.0 ± 0.2

66.2 ± 2.9

87.0 ± 0.4

75.0 ± 0.6

80.0 ± 2.5

+

195

77.3 ± 0.5

70.0 ± 0.5

84.5 ± 0.9

60.5 ± 3.2

75.0 ± 0.3

+

118

0.0

0.0

0.0

57.5 ± 0.5

19.3 ± 1.7

003

11.5 ± 1.4

46 ± 1.2

39.0 ± 5.2

66.6 ± 3.0

56.0 ± 2.8

089

0.0

0.0

0.0

0.0

15.5 ± 1.7

062

10.8 ± 1.2

0.0

16.0 ± 2.8

0.0

13.0 ± 2.1

337

12.0 ± 2.3

0.0

74.0 ± 0.6

10.5 ± 0.2

52.0 ± 2.0

  1. aPercent of cells ± SEM exhibiting moderate to strong stain for antibody.
  2. bT1 tumor growth was positive (+) when a nodule at the site of the transplant was visible within 2 weeks. Growth was negative (−) when the tumor was absorbed by host.