Fig. 4
From: The Role of a Single Formin Isoform in the Limb and Renal Phenotypes of Limb Deformity
Whole-mount in situ analysis of isoforms I–III and IV in wild-type and mutant mice
+ /+ (A) and ldGKO/ldGKO (−/−) (B) E11.5 embryos, and dissected mesonephroi from + / + (C) and ldGKO/ldGKO (−/−) (D) E10.5 embryos were hybridized with an isoform I–III RNA antisense probe. +/+ (E) and ldGKO/ldGKO (F) E10.5 embryos, and dissected kidneys from + / + (G) and ldGKO/ldGKO (H) E 13.5 embryos were hybridized with an isoform IV RNA antisense probe. AER, apical ectodermal ridge; S, punctate staining in the somites; DRG, dorsal root ganglia; TG, trigeminal ganglia; Mes, mesonephric tubules; Tu, metanephric tubules (arrowheads); BA, branchial arches.