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Fig. 3 | Molecular Medicine

Fig. 3

From: Multiple Mechanisms Support Oligoclonal T Cell Expansion in Rheumatoid Synovitis

Fig. 3

TCR gene segment usage of joint-specific clones

TCR ß chains from T cell clones which were overrepresented at two different sites of the synovial inflammation, but not in the peripheral blood (as shown in Fig. 2) were identified and clonal identity was confirmed by sequencing of eluted bands. TCR BV (left) and TCR BJ (right) gene segment usage is shown. The T cell response was heterogeneous with a trend towards usage of the BV3 segment.

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