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Fig. 1 | Molecular Medicine

Fig. 1

From: Molecular and Structural Characterization of Five Novel Mutations in the Bruton’s Tyrosine Kinase Gene from Patients with X-Linked Agammaglobulinemia

Fig. 1

Btk coding sequence showing approximate positions of the mutations (bottom) and polymorphisms (top)

The sequence starts at nucleotide 133 and ends at nucleotide 2109. The protein functional domains are indicated by PH (pleckstrin homology), TH (Tec homology), SH3 (Src homology 3), SH2 (Src homology 2), and kinase, respectively. Intronic alterations are noted at the nearest exonic positions.

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Molecular Medicine

ISSN: 1528-3658