Fig. 7

Detection of mature forms of P. falciparum IRBCs in the circulation of monkeys after CSA inoculation

Naive squirrel monkeys (89013, 89014, and 89085) and a P. falciparum preimmune monkey (1808), received one intramuscular injection of 50 mg of CSA dissolved in 1 ml of NaCl 0.9% per kg of body weight during their P. falciparum infection at the day indicated by the black arrow. The open arrow points to the 1 ml intramuscular injection of 0.9% NaCl into the control monkey (8901M) which later received a CSA injection (black arrow). Naive monkey (88052) and a P. falciparum preimmune monkey (1739) received two intramuscular injections of CSA dissolved in NaCl 0.9% (50 mg/kg body weight) during their P. falciparum infection at a 24-hr interval as indicated by the black arrows. The parasitemia of ring stages (□) and mature stages (■) is shown as percentages.