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Table 1 Allele frequencies (±SE) and heterozygosity observed for the four RFLPs among the melanocortin receptor 5 and 4, and the haplotype of MC5R in the Québec Family Study

From: Linkage and Association Studies between the Melanocortin Receptors 4 and 5 Genes and Obesity-Related Phenotypes in the Québec Family Study

Gene

Chromosome

RFLP

Allele

Frequency

Heterozygosity

MC5R

18p11.2a

Haplotypes PstI/PvuII

PstI 5.1/PvuII 5.5

0.842 ± 0.016

0.28

   

PstI 5.1/PvuII 5.1

0.103 ± 0.013

 
   

PstI 3.8/PvuII 5.5

0.049 ± 0.009

 
   

PstI 3.8/PvuII 5.1

0.006 ± 0.003

 
  

PstI

PstI 5.1

0.950 ± 0.009

0.10

   

PstI 3.8

0.050 ± 0.009

 
  

PvuII

PvuII 5.5

0.89 ± 0.01

0.20

   

PvuII 5.1

0.11 ± 0.01

 

MC4R

18q21.3-q22b

NcoI

NcoI 6.3

0.74 ± 0.02

0.38

   

NcoI 5.6

0.26 ± 0.02

 
  1. aref. 35; bref. 28.