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Table 1 Allele frequencies (±SE) and heterozygosity observed for the four RFLPs among the melanocortin receptor 5 and 4, and the haplotype of MC5R in the Québec Family Study

From: Linkage and Association Studies between the Melanocortin Receptors 4 and 5 Genes and Obesity-Related Phenotypes in the Québec Family Study

Gene Chromosome RFLP Allele Frequency Heterozygosity
MC5R 18p11.2a Haplotypes PstI/PvuII PstI 5.1/PvuII 5.5 0.842 ± 0.016 0.28
    PstI 5.1/PvuII 5.1 0.103 ± 0.013  
    PstI 3.8/PvuII 5.5 0.049 ± 0.009  
    PstI 3.8/PvuII 5.1 0.006 ± 0.003  
   PstI PstI 5.1 0.950 ± 0.009 0.10
    PstI 3.8 0.050 ± 0.009  
   PvuII PvuII 5.5 0.89 ± 0.01 0.20
    PvuII 5.1 0.11 ± 0.01  
MC4R 18q21.3-q22b NcoI NcoI 6.3 0.74 ± 0.02 0.38
    NcoI 5.6 0.26 ± 0.02  
  1. aref. 35; bref. 28.