iNOS expression in healthy and pathological skin
(A) PCR showing HPRT (upper lanes) and iNOS bands (lower bands) in 11 patients with acute urticaria (for each patient: healthy skin followed by lesional skin; Patient 4 is negative for iNOs mRNA). (B) iNOS immunoreactivity in pathological skin, showing staining all along the basal layer of keratinocytes. (C) Negative (anti-CD3 moAb) and (D) positive control (anticytokeratin Ab) from the same biopsy. Magnification: ×240 (B), ×60 (C, D).