Immunohistochemical analysis of the temporal neocortex of a sporadic case of AD by FCA 3542 IgG-purified fraction
The temporal neocortex (sporadic AD case) was incubated with a 250-fold dilution of the IgG-purified fraction of FCA3542, then immunoreactivity was revealed by the biotin-streptavidin-peroxidase method. White arrowheads in A, B, and C indicate mature plaques while black arrow in B indicates an immature plaque. Note in D the labeling of the vascular wall of a cortical arteriole. Magnification: A, B, and D, × 200; C, × 400.