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Table 2 Tumor-specific shared antigens

From: Tumor Antigens Discovery: Perspectives for Cancer Therapy

  

Expression patternsa

 

Antigens

HLA restrictions

Normal tissues

Melanoma (%)

Breast (%)

Prostate (%)

Bladder (%)

MAGE-1

HLA-A1, -Cw16

Testis

30

5

15

19

MAGE-3

HLA-A1, -A2

Testis

65

5

15

34

BAGE

HLA-Cw16

Testis

17

10

0

15

GAGE-1

HLA-Cw6

Testis

20

0

10

12

CAG-3/NY-ES0-1

HLA-A31

Testis

35

30

25

80

  1. a Gene expression was assayed by RT-PCR of RNA extracted from tumor samples.