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Table 1 Quantitative analysis of cell morphology in wild-type and in synapsin I, synapsin II, and synapsin I/II double knockout (k.o.) mice

From: Distinct Roles of Synapsin I and Synapsin II during Neuronal Development

Neuronal development (stage)

Wild-type

Synapsin I k.o.

Synapsin II k.o.

Synapsin I/II k.o.

I

3 ± 1

4 ± 1

7 ± 1*

3 ± 1

II

30 ± 2

32 ± 2

85 ± 6*

37 ± 3

III

67 ± 4

64 ± 5

8 ± 1*

60 ± 4

  1. Embryonic E16 hippocampal cultures were prepared as described (11,17). Twenty-four hr after plating, cells were fixed and stained with a tubulin antibody and their morphology analyzed in 20 fields from three different experiments.
  2. Values are given as percent of total. Each number represents the mean ± SEM. *Differs from wild-type P < 0.001.
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Molecular Medicine

ISSN: 1528-3658