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Table 1 Internalization of PA-c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies on 9E10 hybridoma cells

From: Internalization of a Bacillus anthracis Protective Antigen-c-Myc Fusion Protein Mediated by Cell Surface Anti-c-Myc Antibodies

   

EC 50 in ng/mL a

 

Toxin

With Competitor

With c-Myc Peptide b

With PA SNKEΔFF c

With c-Myc Peptide b and PA SNKEΔFF c

PA-c-Myc

50

10

100

>1000

PA

30

10

>1000

>1000

  1. aEC50 is the concentration of toxin required to kill half of the cells compared with untreated controls. EC50 values are interpolated from Fig. 4A and B. bc-Myc peptide was used at 5.5 µg/ml. cPA SNKEΔFF was used at 20 µg/ml.
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Molecular Medicine

ISSN: 1528-3658