Fig. 3
Aβ induces monocyte secretion of chemokines. Monocytes (5 × 105) were cultivated in RPMI medium with 10% autologous serum in the presence of indicated concentrations of Aβ. Media were harvested 48 hr later and the concentrations of (A) MIP-1α, (B) MCP-1, and (C) IL-8 were determined by the chemokine ELISA assay. *, post-hoc analysis (Fisher’s LSD) significantly different from Aβ 0.5 and 5 µg/ml, p < 0.05.