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Fig. 1 | Molecular Medicine

Fig. 1

From: Frequent N Addition and Clonal Relatedness among Immunoglobulin Lambda Light Chains Expressed in Rheumatoid Arthritis Synovia and PBL, and the Influence of Vλ Gene Segment Utilization on CDR3 Length

Fig. 1

(A) Sequences of oligonucleotides used as primers and probes. Parentheses indicate sites of degeneracy. RSS, recombination signal sequence; FR2, framework 2. (B) Comparison of VλIIIa, b, and c leader sequences and primers used for RT-PCR to the germline humlv318 sequence. Dots indicate nucleotide sequence homology. Underlined sequences indicate EcoRI restriction sites. (C) Sequences of RSS of gene segments IGLV3S2, lv318, and III.1.

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