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Table 1C Germline derivation of J λ gene segments in cDNA clones

From: Frequent N Addition and Clonal Relatedness among Immunoglobulin Lambda Light Chains Expressed in Rheumatoid Arthritis Synovia and PBL, and the Influence of Vλ Gene Segment Utilization on CDR3 Length

 

Rheumatoid Arthritis

Normal

 

Gene Segment

AS Synovium

AS PBL

BC Synovium

BC PBL

LB PBL

IT PBL

LK PBL

Total

Jλ1

6 (20.0%)

9 (40.9%)

6 (28.6%)

13 (65.0%)

6 (33.3%)

12 (42.8%)

7 (36.8%)

59 (37.3%)

Jλ2

11 (36.7%)

9 (40.9%)

13 (61.9%)

4 (20.0%)

7 (38.9%)

8 (28.6%)

6 (31.6%)

58 (36.7%)

Jλ3

13 (43.3%)

4 (18.2%)

2 (9.5%)

3 (15.0%)

5 (27.7%)

8 (28.6%)

6 (31.6%)

41 (26.0%)

Total

30

22

21

20

18

28

19

158