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Table 3 Cross-reactivity between peptide 65–85 of mycobacterial HSP65 and peptide 90–110 of human HSP63 protein

From: T Cells Recognize an Immunodominant Epitope of Heat Shock Protein 65 in Kawasaki Disease

Mycobacterial HSP65 Peptides

Number (%) of HSP65 Clones Recognizing:

CD4+ Clones

CD8+ Clones

65–85

35/38 (92)

24/28 (86)

69–85

35/38 (92)

0/28 (0)

70–85

35/38 (92)

0/28 (0)

Human HSP63 Peptide

90–110

23/38 (60%)

21/28 (75%)

  1. Results indicate the number (%) of HSP65-specific T-cell clones from KD patients, recognizing both mycobacterial HSP65-derived peptides and human HSP63-derived peptide. (See also the legend to Table 2). HSP65, heat shock protein 65.
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Molecular Medicine

ISSN: 1528-3658