Cytotoxicity of IL-4(38-37)-PE38KDEL on AIDS-KS cells
KS248 and NCB-59 cells (104 cells of each) were cultured in 96-well microtiter plates with the indicated concentration of IL-4 toxin in the absence (◯) and presence of 2 µg/ml of either IL-4 (●) or IL-13 (◼). After 20 hr, cells were pulsed with [3H]leucine (1 µCi per well) for 4 hr and harvested to determine the inhibition in the protein synthesis. Error bars represent the S.D. of quadruplicate determination.