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Fig. 5 | Molecular Medicine

Fig. 5

From: Interleukin-4 Receptor Expression on AIDS-Associated Kaposi’s Sarcoma Cells and Their Targeting by a Chimeric Protein Comprised of Circularly Permuted Interleukin-4 and Pseudomonas Exotoxin

Fig. 5

Cytotoxicity of IL-4(38-37)-PE38KDEL on AIDS-KS cells

KS248 and NCB-59 cells (104 cells of each) were cultured in 96-well microtiter plates with the indicated concentration of IL-4 toxin in the absence () and presence of 2 µg/ml of either IL-4 () or IL-13 (). After 20 hr, cells were pulsed with [3H]leucine (1 µCi per well) for 4 hr and harvested to determine the inhibition in the protein synthesis. Error bars represent the S.D. of quadruplicate determination.

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