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Table 1 IL-4 receptor expression on AIDS-KS cells determined by 125 I-IL-4 binding studies

From: Interleukin-4 Receptor Expression on AIDS-Associated Kaposi’s Sarcoma Cells and Their Targeting by a Chimeric Protein Comprised of Circularly Permuted Interleukin-4 and Pseudomonas Exotoxin

Cell type IL-4 binding sites/cell* Kd (pM)
KS248 2643 ± 30 62.8 ± 10.4
NCB-59 2567 ± 35 23.5 ± 4.7
Normal endothelial cells   
HUVEC <50 76.2 ± 12.4
HUAEC <50 b
  1. aBinding sites and receptor affinity (Kd) for each cell type were calculated by the LIGAND program with (39) the data obtained from radioreceptor binding as described in Materials and Methods. The data are presented as the mean no. of molecules/cell ± S.D. of two to four experiments performed in duplicate.
  2. bCould not be calculated.