Cell type | IL-4 binding sites/cell* | Kd (pM) |
---|
AIDS-KS | | |
KS248 | 2643 ± 30 | 62.8 ± 10.4 |
NCB-59 | 2567 ± 35 | 23.5 ± 4.7 |
Normal endothelial cells | | |
HUVEC | <50 | 76.2 ± 12.4 |
HUAEC | <50 | –b |
- aBinding sites and receptor affinity (Kd) for each cell type were calculated by the LIGAND program with (39) the data obtained from radioreceptor binding as described in Materials and Methods. The data are presented as the mean no. of molecules/cell ± S.D. of two to four experiments performed in duplicate.
- bCould not be calculated.