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Table 1 Characteristics of infections genotyped for the MSP-1 and MSP-2 locus in the cohort recruited in Dielmo, Senegal

From: Imbalanced Distribution of Plasmodium falciparum MSP-1 Genotypes Related to Sickle-Cell Trait

   

MSP-1 Genotyping

MSP-2 Genotyping

 

No. of Individuals

No. of Positive Smears

No. PCR+

Total No. of Bands

No. of Bands/Carrier

No. PCR+

Total No. of Bands

No. of Bands/Carrier

Total

77

50

67

224

3.3

60

179

3

≤10 years

26

21

24

106

4.4

23

93

4

>10 years

51

27

43

118

2.7

37

86

2.3

AS

20

11

14

47

3.4

15

33

2.2

AA

57

37

53

177

3.3

45

146

3.2

Bw53 +

22

13

19

59

3.1

14

38

2.7

Bw53−

45

28

41

138

3.4

38

125

3.3

  1. The cohort was stratified by age, hemoglobin type or HLA Bw53 type. No. of positive smears refers to the number of samples with thick blood smears positive for P. falciparum asexual or sexual stages by microscopic examination. No. PCR+ refers to the number of individuals who had a positive PCR for the locus considered. Total No. of bands refers to the sum of PCR fragments detected in all samples for the locus considered. No. of bands/carrier indicates the average number of distinct alleles detected per PCR-positive isolate. Individual MSP-1 and MSP-2 alleles were identified as indicated in Materials and Methods.
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Molecular Medicine

ISSN: 1528-3658