No. of Subjects Positive for Each Individual Allele |
---|
K1 | MAD 20 | RO33 |
---|
430 | 420 | 360 | 310 | 300 | 300 | 290 | 270 | 230 | 220 | 220 |
---|
2 | 17 | 3 | 1 | 2 | 4 | 1 | 1 | 11 | 10 | 33 |
0 | 8 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 8 |
2 | 9 | 2 | 1 | 1 | 4 | 1 | 1 | 10 | 8 | 25 |
- No. of individuals refers to the number of individuals in a particular group. No. of positive smears refers to the number of samples with thick blood smears positive for P. falciparum asexual or sexual stages by microscopic examination. No. of PCR+ refers to the number of individuals who had a MSP-1-positive PCR. Total no. of bands refers to the sum of MSP-1 PCR fragments detected in all samples. No. of bands/carrier indicates the average number of distinct MSP-1 alleles detected per PCR-positive isolate. Individual MSP-1 alleles were identified as indicated in Materials and Methods. The size of the alleles (in bp) is indicated. For each individual allele, the number of samples in which this allele was detected is shown. Statistically significant difference in allele frequency (calculated as number of samples in which this allele has been detected divided by total number of MSP-1 fragments) is indicated in a box.