Fig. 5
From: Induction of Skin Fibrosis in Mice Expressing a Mutated Fibrillin-1 Gene
Histopathology of the skin from pdFbn-1 mice. The plasmid bearing fibrillin-1 gene (pdFbn-1) hi and lo correspond to skin collected from high and low copy number 3- and 6-month-old transgenic (Tg) mice. Skin from two 6-month-old Tg mice are presented in this figure. Low copy number Tg mice were obtained by breeding of founder #1 with C57Bl/6 mice; whereas, high copy number Tg mice were obtained by breeding of founder #3 or 4. All sections were stained with Hematoxyline-eosine (HE) (30X).