Fig. 2
From: Involvement of Macrophage Migration Inhibitory Factor (MIF) in Experimental Uric Acid Nephropathy
Histological changes in urate nephropathy. (A) Normal kidney morphology from an oxonic acid (OA) rat (periodic acid/Schiff reagent; PAS, 200X). (B) Amorphous uric acid and acicular urate crystals within tubules in oxonic acid plus uric acid (UA) group (De Galantha stain 400X). (B) Granuloma formation (*) with central accumulation of crystalloid material surrounded by leukocytes, multinucleated giant cells and fibrosis (PAS stain 200X).