Fig. 5From: Suberoylanilide Hydroxamic Acid as a Potential Therapeutic Agent for Human Breast Cancer TreatmentSAHA induces DNA fragmentation in human breast cancer cells. MCF7 and MDA-MB-231 cells were treated with dimethylsulfoxide (DMSO) alone (Con), or suberoylanilide hydrox-amic acid (SAHA) at 4 µM for 24 hr, 48 hr, or 72 hr, and then analyzed for DNA fragmentation by laddering analysis. Shown are photographs of ethidium bromide-stained gels.Back to article page