Fig. 4From: Advanced Glycation Endproducts: Activators of Cardiac Remodeling in Primary Fibroblasts From Adult Rat HeartsConcentration dependent stimulation of cellular signaling. Quiescent cardiac fibroblasts were stimulated with indicated amounts of AGE-BSA/BSA for 45 min (ERK-1/2) or 90 min (ATF-2). Cell lysates were prepared and the activation of these proteins analyzed by immunoblotting using phosphospecific antibodies.Back to article page