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Table 2 Association between K-ras and c-mos, K-ras-c-mos and K-ras/c-mos patterns, and MVD and VEGF

From: Relationship of the K-ras/c-mos Expression Patterns With Angiogenesis in Non-Small Cell Lung Carcinomas

 

MVD (microvessels/mm2)

VEGF (%)

Alteration (number of cases)

Mean

StDev

p

Mean

StDev

p a

K-ras

 

No (37)

A (12)

37.6

38.0

11.1

4.8

0.801b

71.7

73.4

21.7

20.4

0.801

c-mos

 

N (45)

P (16)

39.0

29.9

9.8

10.8

0.003c

77.4

63.4

16.8

24.5

0.045

K-ras-c-mosd

 

No (24)

Ab (25)

40.7

33.4

10.8

9.6

0.012c

76.9

67.5

17.4

23.2

0.168

K-ras/c-mose

 

No/N (24)

A/N (11)

No/P (13)

40.7

38.0

29.3

10.8

5.2

10.9

0.004f

76.9

75.9

62.3

17.4

19.3

25.0

0.157

  1. aKruskal-Wallis test.
  2. bKruskal-Wallis test; p = 0.03 by F-test.
  3. ct-test
  4. dCategorization based on the complete absence or presence of at least one aberration in K-ras or c-mos (see Results section 4).
  5. eCategorization into groups according to K-ras and c-mos status (see Results section 4).
  6. fANOVA, p = 0.003 between No/P and No/N patterns and p = 1.000 between A/N and No/N, by Bonferroni analysis. A, activated; No, normal; N, negative; P, positive; Ab, aberrant.
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Molecular Medicine

ISSN: 1528-3658