Fig. 5From: The Regulation and Localization of Angiopoietin-1, -2, and Their Receptor Tie2 in Normal and Pathologic Human PlacentaeThe ratio of mRNAs encoding Ang-1 and Ang-2 in response to reduced oxygen in first trimester (A) and term (B) villous cultures. In the first trimester, the change of Ang-l/Ang-2 ratio was not significant in response to reduced oxygen while at term it decreased 8-fold. *Paired student t test, n = 3, t = 6.1655, p = 0.025. â–¡ ambient oxygen; â– reduced oxygen.Back to article page