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Fig. 3 | Molecular Medicine

Fig. 3

From: Administration of Neutralizing Antibodies to Interleukin-6 (IL-6) Reduces Experimental Autoimmune Encephalomyelitis and Is Associated with Elevated Levels of IL-6 Bioactivity in Central Nervous System and Circulation

Fig. 3

Relationship between levels of IL-6 and anti-IL-6 Ab in serum and CSF, and EAE expression

IL-6 and anti-IL-6 Ab data are from Fig. 4 and Table 3. The data regarding IL-6 levels and clinical and histological disease are from the same experiment. EAE was scored clinically as described in Materials and Methods. Histology was scored as either + or −, depending on the presence or absence, respectively, of inflammatory infiltrates and demyelination in the CNS. n.d., not determined.

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